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Basic Energy Concepts
Types of Catabolism
Catabolism of Fats
Catabolism of Proteins
Summary of Catabolism
Assembly of Stuctures
©2000 Timothy Paustian, University of Wisconsin-Madison
Often, once the polymers are formed they will correctly self assemble into the macromolecular structures. The information necessary for biopolymers to come together into the structures of the cells is encoded in their primary sequence. Here are a few examples
The take home message is that many cell polymers know how to assemble into structures. From an evolutionary standpoint this makes sense. Primitive self replicating molecules probably organized themselves into structures using the simplest mechanism possible - self assembly. As more complex organisms evolved, this method continued to hold sway due to its elegance.
After saying all of this, I am now going to contradict myself. Recent work has shown there are proteins in high concentration that seem to assist many of these assembly processes, guiding the polymers down the correct path, destroying aberrant assemblies and increasing efficiency. As higher life forms (bacteria) evolved it became worthwhile to create proteins to increase the chances of getting successful macromolecules built. The term molecular chaperons has been coined to describe these molecules. It seems as if all living organisms contain proteins that carry out these guiding functions.
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